Gene information
Official symbol TXNRD2
Official full name thioredoxin reductase 2
Gene type protein-coding gene
Chromosome22q11.21
Alias symbolTR; TRXR2; TR3; SELZ
Gene familySelenoproteins
Resources
Entrez Gene 10587
HGNC HGNC:18155
Ensembl ENSG00000184470
Vega OTTHUMG00000149975
UCSC uc021wlj.4
GO terms: 19 records
GO Description Category LogP Number of genes Detail
GO:0000302 response to reactive oxygen species GO Biological Processes -13.4775134 34 More
GO:0006979 response to oxidative stress GO Biological Processes -17.6147653 58 More
GO:0009410 response to xenobiotic stimulus GO Biological Processes -32.6021211 82 More
GO:0009636 response to toxic substance GO Biological Processes -18.1818984 46 More
GO:0010035 response to inorganic substance GO Biological Processes -29.1720710 89 More
GO:0016209 antioxidant activity GO Molecular Functions -11.3593886 22 More
GO:0016491 oxidoreductase activity GO Molecular Functions -14.1519969 39 More
GO:0019725 cellular homeostasis GO Biological Processes -21.1508273 85 More
GO:0030424 axon GO Cellular Components -6.14132550 54 More
GO:0030425 dendrite GO Cellular Components -4.55233052 48 More
GO:0042803 protein homodimerization activity GO Molecular Functions -14.2815375 77 More
GO:0043025 neuronal cell body GO Cellular Components -9.18558636 52 More
GO:0044297 cell body GO Cellular Components -11.7206640 62 More
GO:0070482 response to oxygen levels GO Biological Processes -40.7566635 82 More
GO:0097237 cellular response to toxic substance GO Biological Processes -13.7473733 28 More
GO:0097447 dendritic tree GO Cellular Components -4.82959150 49 More
GO:0098754 detoxification GO Biological Processes -12.4136065 17 More
GO:0098869 cellular oxidant detoxification GO Biological Processes -12.6410846 24 More
GO:1990748 cellular detoxification GO Biological Processes -12.8821364 16 More
KEGG pathways: 2 records
KEGG Description Category LogP Number of genes Detail
hsa05200 Pathways in cancer KEGG Pathway -30.6393212 92 More
hsa05225 Hepatocellular carcinoma KEGG Pathway -5.07719186 21 More
Drug-Gene interaction
view
Related drugs: 2 records
Drug name Interaction type Source PMID View
arsenic trioxide DTC 17640917 view
methadone PharmGKB 32407152 view
Related study: 1 record
Molecular factor Omics type Application Objective MI type Reference
NM_006440.5:c.50964T>C genomics myocardial infarction[diagnosis] myocardial infarction Kariz S et al. Diabetes Res Clin Pract. 2015
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